Hervé Falet, Ph.D.

Selected Papers

Arp2/3 complex-deficient mouse fibroblasts are viable and have normal leading edge structure and function. Di Nardo A, Cicchetti G, Falet H, Hartwig JH, Stossel TP, Kwiatkowski DJ. Proc Natl Acad Sci USA 102, 16263-16268, 2005   

IIb3 signals lead cofilin to accelerate platelet actin dynamics. Falet H, Chang G, Brohard-Bohn B, Rendu F, Hartwig JH. Am J Physiol Cell Physiol 289, C819-C825, 2005   

WIP regulates signaling via the high affinity receptor for immunoglobulin E in mast cells. Kettner A, Kumar L, Antón IM, Sasahara Y, de la Fuente M, Pivniouk VI, Falet H, Hartwig JH, Geha RS. J Exp Med 199, 357-368, 2004   

Structural requirements of SLP-76 in signaling via the high-affinity IgE receptor (FcRI) in mast cells. Kettner A, Pivniouk VI, Kumar L, Falet H, Lee JS, Mulligan R, Geha RS. Mol Cell Biol 23, 2395-2406, 2003   

Mechanisms and implications of platelet discoid shape. Italiano JE Jr, Bergmeier W, Tiwari S, Falet H, Hartwig JH, Hoffmeister K, André P, Wagner DD, Shivdasani RA. Blood 101, 4789-4796, 2003   

The clearance mechanism of chilled blood platelets. Hoffmeister KM, Felbinger TW, Falet H, Denis CV, Bergmeier W, Mayadas TN, von Andrian UH, Wagner DD, Stossel TP, Hartwig JH. Cell 112, 87-97, 2003   

Importance of free actin filament barbed ends for Arp2/3 complex function in platelets and fibroblasts. Falet H, Hoffmeister KM, Neujahr R, Italiano JE Jr, Stossel TP, Southwick FS, Hartwig JH. Proc Natl Acad Sci USA 99, 16782-16787, 2002   

Normal Arp2/3 complex activation in platelets lacking WASp. Falet H, Hoffmeister KM, Neujahr R, Hartwig JH. Blood 100, 2113-2122, 2002   

Book Chapters

Platelet glycoproteins as lectins in hematology. Falet H, Hoffmeister KM. In: The Sugar Code: Fundamentals of Glycosciences. Gabius HJ, Ed. Wiley-VCH, Weinheim. In press

Dynamics of the platelet cytoskeleton. Barkalow KL, Falet H, Hartwig JH. In: Platelets in Thrombotic and Non-Thrombotic Disorders: Pathophysiology, Pharmacology and Therapeutics. Gresele P, Page C, Fuster V, Vermylen J, Eds. Cambridge University Press, Cambridge. pp. 93-103, 2002
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