Fumi Nakamura Ph.D.

Selected Papers

1. Feng Y, Chen MH, Moskowitz IP, Mendonza AM, Vidali L, Nakamura F, et
al. Filamin A (FLNA) is required for cell-cell contact in vascular
development and cardiac morphogenesis. Proc Natl Acad Sci U S A
2006;103(52):19836-41.
2. Gardel ML, Nakamura F, Hartwig J, Crocker JC, Stossel TP, Weitz DA.
Stress-dependent elasticity of composite actin networks as a model for cell
behavior. Phys Rev Lett 2006;96(8):088102.
3. Gardel ML, Nakamura F, Hartwig JH, Crocker JC, Stossel TP, Weitz DA.
Prestressed F-actin networks cross-linked by hinged filamins replicate
mechanical properties of cells. Proc Natl Acad Sci U S A 2006;103(6):1762-7.
4. Nakamura F, Pudas R, Heikkinen O, Permi P, Kilpelainen I, Munday AD,
et al. The structure of the GPIb-filamin A complex. Blood
2006;107(5):1925-32.
5. Sarkisian MR, Bartley CM, Chi H, Nakamura F, Hashimoto-Torii K, Torii
M, et al. MEKK4 signaling regulates filamin expression and neuronal
migration. Neuron 2006;52(5):789-801.
6. Nakamura F, Osborn TM, Hartemink CA, Hartwig JH, Stossel TP.
Structural basis of filamin A functions. J Cell Biol 2007;179(5):1011-25.
7. Weins A, Schlondorff JS, Nakamura F, Denker BM, Hartwig JH, Stossel
TP, et al. Disease-associated mutant {alpha}-actinin-4 reveals a mechanism
for regulating its F-actin-binding affinity. Proc Natl Acad Sci U S A
2007;104(41):16080-16085.
8. Ferrer JM, Lee H, Chen J, Pelz B, Nakamura F, Kamm RD, et al.
Measuring molecular rupture forces between single actin filaments and
actin-binding proteins. Proc Natl Acad Sci U S A 2008;105(27):9221-6.
9. Adamovich DA, Nakamura F, Worth A, Burns S, Thrasher AJ, Hartwig JH,
et al. Activating mutations of N-WASP alter Shigella pathogenesis. Biochem
Biophys Res Commun 2009;384(3):284-9.
10. Kasza KE, Koenderink GH, Lin YC, Broedersz CP, Messner W, Nakamura F,
et al. Nonlinear elasticity of stiff biopolymers connected by flexible
linkers. Physical Review E. 2009;79:041928-1-5.
11. Kasza KE, Nakamura F, Hu S, Kollmannsberger P, Bonakdar N, Fabry B,
et al. Filamin A is essential for active cell stiffening but not passive
stiffening under external force. Biophys J 2009;96(10):4326-35.
12. Li C, Yu S, Nakamura F, Yin S, Xu J, Petrolla AA, et al. Binding of
pro-prion to filamin A disrupts cytoskeleton and correlates with poor
prognosis in pancreatic cancer. Journal of Clinical Investigation 2009;In
press.
13. Nakamura F, Heikkinen O, Pentikainen OT, Osborn TM, Kasza KE, Weitz
DA, et al. Molecular basis of filamin A-FilGAP interaction and its
impairment in congenital disorders associated with filamin A mutations. PLoS
ONE 2009;4(3):e4928.